| Code | Faculty | Department |
|---|---|---|
| 02133402 | Faculty of Natural and Agricultural Sciences | Department: Genetics |
| Credits | Duration | NQF level |
|---|---|---|
| Minimum duration of study: 3 years | Total credits: 430 | NQF level: 07 |
Those students registered for the BSc (Genetics) programme and who have opted to select any of the dual major fields of study offered within this programme must take note of the following:
Bachelor of Science
Genetics
Important information for all prospective students for 2023
The admission requirements below apply to all who apply for admission to the University of Pretoria with a National Senior Certificate (NSC) and Independent Examination Board (IEB) qualifications. Click here for this Faculty Brochure.
Minimum requirements | |||
Achievement level | |||
English Home Language or English First Additional Language | Mathematics | Physical Sciences | APS |
NSC/IEB | NSC/IEB | NSC/IEB | |
5 | 5 | 5 | 32 |
Life Orientation is excluded when calculating the APS.
You will be considered for final admission to degree studies if space allows, and if you have a National Senior Certificate (NSC) or equivalent qualification with admission to bachelor’s degree studies, and comply with the minimum subject requirements as well as the APS requirements of your chosen programme.
Applicants with qualifications other than the abovementioned should refer to the Brochure: Undergraduate Programme Information 2023: Qualifications other than the NSC and IEB, available at click here.
International students: Click here.
Transferring students
A transferring student is a student who, at the time of applying at the University of Pretoria (UP) is/was a registered student at another tertiary institution. A transferring student will be considered for admission based on NSC or equivalent qualification and previous academic performance. Students who have been dismissed from other institutions due to poor academic performance will not be considered for admission to UP.
Closing dates: Same as above.
Returning students
A returning student is a student who, at the time of application for a degree programme is/was a registered student at UP, and wants to transfer to another degree at UP. A returning student will be considered for admission based on NSC or equivalent qualification and previous academic performance.
Note:
Closing date for applications from returning students
Unless capacity allows for an extension of the closing date, applications from returning students must be submitted before the end of August via your UP Student Centre.
Candidates who do not comply with the minimum admission requirements for BSc (Genetics), may be considered for admission to the BSc – Extended programme – Biological and Agricultural Sciences, which requires an additional year of study.
BSc – Extended Programme – Biological and Agricultural Sciences Minimum requirements | |||
Achievement level | |||
English Home Language or English First Additional Language | Mathematics | Physical Sciences | APS |
NSC/IEB | NSC/IEB | NSC/IEB | |
4 | 4 | 4 | 26 |
Note:
*The BSc – Extended programmes are not available for students who meet all the requirements for the corresponding mainstream programme.
*Please note that only students who apply in their final NSC or equivalent qualification year will be considered for admission into any of the BSc – Extended programmes. Students who are upgrading or taking a gap year will not be considered.
1.1 Requirements for specific modules
A candidate who:
or
or
1.2 Fundamental modules
A student will be promoted to the following year of study if he or she passed 100 credits of the prescribed credits for a year of study, unless the Dean on the recommendation of the relevant head of department decides otherwise. A student who does not comply with the requirements for promotion to the following year of study, retains the credit for the modules already passed and may be admitted by the Dean, on recommendation of the relevant head of department, to modules of the following year of study to a maximum of 48 credits, provided that it will fit in with both the lecture and examination timetable.
General promotion requirements in the faculty
All students whose academic progress is not acceptable can be suspended from further studies.
University of Pretoria Programme Qualification Mix (PQM) verification project
The higher education sector has undergone an extensive alignment to the Higher Education Qualification Sub-Framework (HEQF) across all institutions in South Africa. In order to comply with the HEQSF, all institutions are legally required to participate in a national initiative led by regulatory bodies such as the Department of Higher Education and Training (DHET), the Council on Higher Education (CHE), and the South African Qualifications Authority (SAQA). The University of Pretoria is presently engaged in an ongoing effort to align its qualifications and programmes with the HEQSF criteria. Current and prospective students should take note that changes to UP qualification and programme names, may occur as a result of the HEQSF initiative. Students are advised to contact their faculties if they have any questions.
Minimum credits: 142
Fundamental modules = 14
Core modules = 128
Additional information:
Module content:
Find, evaluate, process, manage and present information resources for academic purposes using appropriate technology.
Module content:
Apply effective search strategies in different technological environments. Demonstrate the ethical and fair use of information resources. Integrate 21st-century communications into the management of academic information.
Module content:
The module aims to equip students with the ability to cope with the reading and writing demands of scientific disciplines.
Module content:
Simple statistical analysis: Data collection and analysis: Samples, tabulation, graphical representation, describing location, spread and skewness. Introductory probability and distribution theory. Sampling distributions and the central limit theorem. Statistical inference: Basic principles, estimation and testing in the one- and two-sample cases (parametric and non-parametric). Introduction to experimental design. One- and twoway designs, randomised blocks. Multiple statistical analysis: Bivariate data sets: Curve fitting (linear and non-linear), growth curves. Statistical inference in the simple regression case. Categorical analysis: Testing goodness of fit and contingency tables. Multiple regression and correlation: Fitting and testing of models. Residual analysis. Computer literacy: Use of computer packages in data analysis and report writing.
Module content:
Botanical principles of structure and function; diversity of plants; introductory plant systematics and evolution; role of plants in agriculture and food security; principles and applications of plant biotechnology; economical and valuable medicinal products derived from plants; basic principles of plant ecology and their application in conservation and biodiversity management.
This content aligns with the United Nation's Sustainable Debelopment Goals of No Poverty, Good Health and Well-being, Climate Action, Responsible Consumption and Production, and Life on Land.
Module content:
General introduction to inorganic, analytical and physical chemistry. Atomic structure and periodicity. Molecular structure and chemical bonding using the VSEOR model. Nomenclature of inorganic ions and compounds. Classification of reactions: precipitation, acid-base, redox reactions and gas-forming reactions. Mole concept and stoichiometric calculations concerning chemical formulas and chemical reactions. Principles of reactivity: energy and chemical reactions. Physical behaviour gases, liquids, solids and solutions and the role of intermolecular forces. Rate of reactions: Introduction to chemical kinetics.
Module content:
Theory: General physical-analytical chemistry: Chemical equilibrium, acids and bases, buffers, solubility equilibrium, entropy and free energy, electrochemistry. Organic chemistry: Structure (bonding), nomenclature, isomerism, introductory stereochemistry, introduction to chemical reactions and chemical properties of organic compounds and biological compounds, i.e. carbohydrates and aminoacids. Practical: Molecular structure (model building), synthesis and properties of simple organic compounds.
Module content:
Chromosomes and cell division. Principles of Mendelian inheritance: locus and alleles, dominance interactions, extensions and modifications of basic principles.. Probability studies. Sex determination and sex linked traits. Pedigree analysis. Genetic linkage and chromosome mapping. Chromosome variation.
Module content:
The module will introduce the student to the field of Microbiology. Basic Microbiological aspects that will be covered include introduction into the diversity of the microbial world (bacteria, archaea, eukaryotic microorganisms and viruses), basic principles of cell structure and function, microbial nutrition and microbial growth and growth control. Applications in Microbiology will be illustrated by specific examples i.e. bioremediation, animal-microbial symbiosis, plant-microbial symbiosis and the use of microorganisms in industrial microbiology. Wastewater treatment, microbial diseases and food will be introduced using specific examples.
Module content:
Introduction to the molecular structure and function of the cell. Basic chemistry of the cell. Structure and composition of prokaryotic and eukaryotic cells. Ultrastructure and function of cellular organelles, membranes and the cytoskeleton. General principles of energy, enzymes and cell metabolism. Selected processes, e.g. glycolysis, respiration and/or photosynthesis. Introduction to molecular genetics: DNA structure and replication, transcription, translation. Cell growth and cell division.
Module content:
Note: PHY 131 is aimed at students who will not continue with physics. PHY 131 cannot be used as a substitute for PHY 114.
Units, vectors, one dimensional kinematics, dynamics, work, equilibrium, sound, liquids, heat, thermodynamic processes, electric potential and capacitance, direct current and alternating current, optics, modern physics, radioactivity.
Module content:
*Students will not be credited for more than one of the following modules for their degree: WTW 134, WTW 165, WTW 114, WTW 158. WTW 134 does not lead to admission to Mathematics at 200 level and is intended for students who require Mathematics at 100 level only. WTW 134 is offered as WTW 165 in the second semester only to students who have applied in the first semester of the current year for the approximately 65 MBChB, or the 5-6 BChD places becoming available in the second semester and who were therefore enrolled for MGW 112 in the first semester of the current year.
Functions, derivatives, interpretation of the derivative, rules of differentiation, applications of differentiation, integration, interpretation of the definite integral, applications of integration. Matrices, solutions of systems of equations. All topics are studied in the context of applications.
Module content:
*Students will not be credited for more than one of the following modules for their degree: WTW 134, WTW 165, WTW 114, WTW 158. WTW 165 does not lead to Mathematics at 200 level and is intended for students who require Mathematics at 100 level only. WTW 165 is offered in English in the second semester only to students who have applied in the first semester of the current year for the approximately 65 MBChB, or the 5-6 BChD places becoming available in the second semester and who were therefore enrolled for MGW 112 in the first semester of the current year.
Functions, derivatives, interpretation of the derivative, rules of differentiation, applications of differentiation, integration, interpretation of the definite integral, applications of integration, matrices, solutions of systems of equations. All topics are studied in the context of applications.
Module content:
Animal classification, phylogeny organisation and terminology. Evolution of the various animal phyla, morphological characteristics and life cycles of parasitic and non-parasitic animals. Structure and function of reproductive,
respiratory, excretory, circulatory and digestive systems in various animal phyla. In-class discussion will address the sustainable development goals #3, 12, 13, 14 and 15 (Good Health and Well-being. Responsible Consumption and Production, Climate Action, Life Below Water, Life on Land).
Minimum credits: 144
Core modules = 84
Elective modules = 60
Additional information:
Single major track:
Dual major track:
Module content:
Structural and ionic properties of amino acids. Peptides, the peptide bond, primary, secondary, tertiary and quaternary structure of proteins. Interactions that stabilise protein structure, denaturation and renaturation of proteins. Introduction to methods for the purification of proteins, amino acid composition, and sequence determinations. Enzyme kinetics and enzyme inhibition. Allosteric enzymes, regulation of enzyme activity, active centres and mechanisms of enzyme catalysis. Examples of industrial applications of enzymes and in clinical pathology as biomarkers of diseases. Online activities include introduction to practical laboratory techniques and Good Laboratory Practice; techniques for the quantitative and qualitative analysis of biological molecules; enzyme activity measurements; processing and presentation of scientific data.
Module content:
Carbohydrate structure and function. Blood glucose measurement in the diagnosis and treatment of diabetes. Bioenergetics and biochemical reaction types. Glycolysis, gluconeogenesis, glycogen metabolism, pentose phosphate pathway, citric acid cycle and electron transport. Total ATP yield from the complete oxidation of glucose. A comparison of cellular respiration and photosynthesis. Online activities include techniques for the study and analysis of metabolic pathways and enzymes; PO ratio of mitochondria, electrophoresis, extraction, solubility and gel permeation techniques; scientific method and design.
Module content:
Chemical foundations. Weak interactions in aqueous systems. Ionisation of water, weak acids and weak bases. Buffering against pH changes in biological systems. Water as a reactant and function of water. Carbohydrate structure and function. Biochemistry of lipids and membrane structure. Nucleotides and nucleic acids. Other functions of nucleotides: energy carriers, components of enzyme cofactors and chemical messengers. Introduction to metabolism. Bioenergetics and biochemical reaction types. Online activities include introduction to laboratory safety and Good Laboratory Practice; basic biochemical calculations; experimental method design and scientific controls, processing and presentation of scientific data.
Module content:
The chemical nature of DNA. The processes of DNA replication, transcription, RNA processing, translation. Control of gene expression in prokaryotes and eukaryotes. Recombinant DNA technology and its applications in gene analysis and manipulation.
Module content:
Chromosome structure and transposable elements. Mutation and DNA repair. Genomics and proteomics. Organelle genomes. Introduction to genetic analysis of populations: allele and genotypic frequencies, Hardy Weinberg Law, its extensions and implications for different mating systems. Introduction to quantitative and evolutionary genetics.
Module content:
Growth, replication and survival of bacteria, Energy sources, harvesting from light versus oxidation, regulation of catabolic pathways, chemotaxis. Nitrogen metabolism, iron-scavenging. Alternative electron acceptors: denitrification, sulphate reduction, methanogenesis. Bacterial evolution, systematic and genomics. Biodiversity; bacteria occurring in the natural environment (soil, water and air), associated with humans, animals, plants, and those of importance in foods and in the water industry.
Module content:
Organisation and molecular architecture of fungal thalli, chemistry of the fungal cell. Chemical and physiological requirements for growth and nutrient acquisition. Mating and meiosis; spore development; spore dormancy, dispersal and germination. Fungi as saprobes in soil, air, plant, aquatic and marine ecosystems; role of fungi as decomposers and in the deterioration of materials; fungi as predators and parasites; mycoses, mycetisms and mycotoxicoses; fungi as symbionts of plants, insects and animals. Applications of fungi in biotechnology.
Module content:
Biochemistry of lipids, membrane structure, anabolism and catabolism of lipids. Total ATP yield from the complete catabolism of lipids. Electron transport chain and energy production through oxidative phosphorylation. Nitrogen metabolism, amino acid biosynthesis and catabolism. Biosynthesis of neurotransmitters, pigments, hormones and nucleotides from amino acids. Catabolism of purines and pyrimidines. Therapeutic agents directed against nucleotide metabolism. Examples of inborn errors of metabolism of nitrogen containing compounds. The urea cycle, nitrogen excretion. Online activities include training in scientific reading skills; evaluation of a scientific report; techniques for separation analysis and visualisation of biological molecules; hypothesis design and testing, method design and scientific controls.
Module content:
Origin and affinity of South African flora and vegetation types; principles of plant geography; plant diversity in southern Africa; characteristics, environments and vegetation of South African biomes and associated key ecological processes; centra of plant endemism; rare and threatened plant species; biodiversity conservation and ecosystem management; invasion biology; conservation status of South African vegetation types.
Module content:
Nitrogen metabolism in plants; nitrogen fixation in Agriculture; plant secondary metabolism and natural products; photosynthesis and carbohydrate metabolism in plants; applications in solar energy; plant growth regulation and the Green Revolution; plant responses to the environment; developing abiotic stress tolerant and disease resistant plants. Practicals: Basic laboratory skills in plant physiology; techniques used to investigate nitrogen metabolism, carbohydrate metabolism, pigment analysis, water transport in plant tissue and response of plants to hormone treatments.
Module content:
Theory: Classical chemical thermodynamics, gases, first and second law and applications, physical changes of pure materials and simple compounds. Phase rule: Chemical reactions, chemical kinetics, rates of reactions.
Module content:
Statistical evaluation of data in line with ethical practice, gravimetric analysis, aqueous solution chemistry, chemical equilibrium, precipitation-, neutralisation- and complex formation titrations, redox titrations, potentiometric methods, introduction to electrochemistry. Examples throughout the course demonstrate the relevance of the theory to meeting the sustainable development goals of clean water and clean, affordable energy.
Module content:
Resonance, conjugation and aromaticity. Acidity and basicity. Introduction to 13C NMR spectroscopy. Electrophilic addition: alkenes. Nucleophilic substitution, elimination, addition: alkyl halides, alcohols, ethers, epoxides, carbonyl compounds: ketones, aldehydes, carboxylic acids and their derivatives Training in an ethical approach to safety that protects self, others and the environment is integral to the practical component of the course.
Module content:
Atomic structure, structure of solids (ionic model). Coordination chemistry of transition metals: Oxidation states of transition metals, ligands, stereochemistry, crystal field theory, consequences of d-orbital splitting, chemistry of the main group elements, electrochemical properties of transition metals in aqueous solution, industrial applications of transition metals. Fundamentals of spectroscopy and introduction to IR spectroscopy. During practical training students learn to acquire and report data ethically. Practical training also deals with the misuse of chemicals and appropriate waste disposal to protect the environment and meet the UN sustainable development goals.
Module content:
Note: Enrolment is limited. Preference will be given based on choice of majors. Students should enquire at the department if they wish to register for the module, but are unable to do so.
*GIS 221 does not lead to admission to any module at 300 level.
Introduction to Geographic Information Systems (GIS), theoretical concepts and applications of GIS. The focus will be on the GIS process of data input, data analysis, data output and associated technologies.This module teaches students to use GIS as a tool. Examples used throughout the course are drawn from South African case studies.
Module content:
Primary sources of migroorganisims in food. Factors affecting the growth and survival of microorganisms in food. Microbial quality, spoilage and safety of food. Different organisms involved, their isolation, screening and detection. Conventional approaches, alternative methods rapid methods. Food fermentations: fermentation types, principles and organisms involved.
Module content:
Fundamental principles of plant pathology. The concept of disease in plants. Causes of plant diseases. Stages in development of plant diseases. Disease cycles and selected examples relevant to Africa. Diagnosis of plant diseases and the sustainable development goals that articulate with plant pathology.
Module content:
Origin and extent of modern invertebrate diversity; parasites of man and domestic animals; biology and medical importance of arachnids and insects; insect life styles; the influence of the environment on insect life histories; insect herbivory; predation and parasitism; insect chemical, visual, and auditory communication. Examples used in the module are relevant to the sustainable development goals of Life on Land and Good Health and Well-being.
Module content:
Introduction to general vertebrate diversity; African vertebrate diversity; vertebrate structure and function; vertebrate evolution; vertebrate relationships; aquatic vertebrates; terrestrial ectotherms; terrestrial endotherms; vertebrate characteristics; classification; structural adaptations; habits; habitats; conservation problems; impact of humans on other vertebrates. The module addresses the sustainable development goals of Life below Water and Life on Land.
Minimum credits: 144
Core = 54
Elective = 90
Additional information:
Single major track:
Dual major track:
Module content:
Regulation of gene expression in eukaryotes: regulation at the genome, transcription, RNA processing and translation levels. DNA elements and protein factors involved in gene control. The role of chromatin structure and epigenetic changes. Technology and experimental approaches used in studying eukaryotic gene control. Applications of the principles of gene control in eg cell signaling pathways, development cancer and other diseases in humans.
Module content:
A unifying framework for biology. Mechanisms involved in the evolution of genes, genomes and species. Comparative genomics across the kingdoms of life. Phylogenetic inference. Applications of phylogenetics and evolutionary genomics research, including relevance to sustainable development goals for food security, good health and the biosphere.
Module content:
Processes that affect genetic evolution: mutation, drift, natural selection and recombination. Fisher-Wright and coalescence models. Groupings of genes: linkage, inbreeding, population structure and gene flow. Neutral and nearly neutral theory. Quantitative genetics and the phenotype. Optimality. Adaptation. Levels of selection in sex ratios and conflict. Reproductive value and life history. Relatedness and kin selection. Sexual reproduction and selection. Genomic complexity and neutrality.
Module content:
Structure, function, bioinformatics and biochemical analysis of (oligo)nucleotides, amino acids, proteins and ligands – and their organisation into hierarchical, higher order, interdependent structures. Principles of structure-function relationships, protein folding, sequence motifs and domains, higher order and supramolecular structure, self-assembly, conjugated proteins, post-translational modifications. Molecular recognition between proteins, ligands, DNA and RNA or any combinations. The RNA structural world, RNAi, miRNA and ribosomes. Cellular functions of coding and non-coding nucleic acids. Basic principles of mass spectrometry, nuclear magnetic resonance spectroscopy, X-ray crystallography and proteomics. Protein purification and characterisation including, pI, molecular mass, amino acid composition and sequence. Mechanistic aspects and regulation of information flow from DNA via RNA to proteins and back. Practical training includes hands-on nucleic acid purification and sequencing, protein production and purification, analysis by SDS-PAGE or mass spectrometry, protein structure analysis and 3D protein modelling.
Module content:
Regulation of metabolic pathways. Analysis of metabolic control. Elucidation of metabolic pathways with isotopes. Metabolomics. Coordinated regulation of glycolysis/gluconeogenesis and glycogen breakdown/synthesis. Overview of homone action. Metabolism of xenobiotics. Hormonal regulation of feul metabolism. Metabolic adaptions during diabetes. Obesity and the regulation of body mass. Obesity, metabolic syndrome and Type 2 diabetes (T2D). Management of T2D with diet, exercise and medication. Practical sessions cover tutorials on case studies and biochemical calculations, and hands-on isolation of an enzyme, determination of pH and temperature optima, determination of Km and Vmax, enzyme activation and enzyme inhibition.
Module content:
Visualising cell structure and localisation of proteins within cells. Cell ultrastructure. Purification of subcellular organelles. Culturing of cells. Biomembrane structure. Transmembrane transport of ions and small molecules and the role of these processes in disease. Moving proteins into membranes and organelles. Vesicular traffic, secretion, exocytosis and endocytosis. Cell organisation and movement motility based on the three types of cytoskeletal structures including microfilaments, microtubules and intermediate filaments as well as their associated motor proteins. Cell-cell and cell-matrix adhesion through corresponding proteins and morphological structures. Practical training includes tutorials on cytometry and microscopy, mini-research projects where students are introduced and guided through aspects of research methodology, experimental planning techniques associated with cellular assays, buffer preparation, active transport studies in yeast cells, structure-function analyses of actin and binding partners.
Module content:
Molecular mechanisms behind exogenous and endogenous diseases. Foundational knowledge of the immune system, with innate-, adaptive- and auto-immunity (molecular mechanisms of the maintenance and failure of the recognition of foreign in the context of self in the mammalian body) being some of the key concepts. Molecular pathology and immunobiochemistry of exogenous diseases against viral, bacterial and parasitic pathogens with a focus on the human immunodeficiency virus (HIV), tuberculosis (TB) and malaria. Endogenous disease will describe the biochemistry of normal cell cycle proliferation, quiescence, senescence, differentiation and apoptosis, and abnormal events as illustrated by cancer. Tutorials will focus on immunoassays, vaccines, diagnostic tests for diseases and drug discovery towards therapeuticals.
Module content:
Introduction to plant ecophysiology and plants response to environmental stress. Understanding how various biotic and abiotic factors affect plant metabolic processes, including photosynthesis and respiration. Emphasis is placed on the efficiency of the mechanisms whereby C3-, C4 and CAM-plants bind CO2 and how they are impacted by the environment. To understand the functioning of plants in diverse environments, the relevant structural properties of plants, the impact of soil composition, water flow in the soil-plant air continuum and long distance transport of assimilates will be discussed. Students will research a topic relevant to plant ecophysiology and present this in the form of an oral presentation. Students will conduct a practical project to study the effects of environmental factors on C3 and C4 plant growth and physiology. Students will present the report in a written format according to the guidelines of a relevant scientific journal. Relevant readings will be used to highlight the alignment of the module with the Sustainable Development Goals, with emphasis placed on climate action.
Module content:
Theory of plant community concepts, floristic and structural composition, plant diversity, ecological succession, landscape ecology. Data processing techniques. Species interactions and an evaluation of their effects on interacting species. Fundamentals of plant population biology: life tables; plant breeding systems and pollination; population dynamics; life history strategies; intraspecific competition; interspecific competition and co-existence. There is a compulsory field-based practical run over a weekend in the first month of the first semester.
Module content:
The module will include a review on the discovery and use of plant medicines and phyto-therapeutically important molecules obtained from plants. Certain aspects of natural product chemistry i.e. the biosynthesis, ecological role and toxicity of the three main classes of secondary compounds; terpenoids, phenolics, and alkaloids are discussed. An introduction to the principles and applications of metabolomics is presented. The role of these natural products in defense against microorganisms and herbivores is reviewed during the module. The importance of ethnobotany and phylogenetics in modern drug discovery from biodiversity will presented along with legal and ethical considerations surrounding bioprospecting. This will follow on with modern theories and practices regarding sustainable utilisation and conservation of medicinal plants. The basics of alternative medicines, with an emphasis on traditional African and Chinese medicines, are also discussed as well as current evidence-based research and product development derived from these. Biotechnological approaches to medicinal natural product production, ‘farmer to pharma’, will be covered, including plant cell culture and bioreactors. Practical sessions on drug discovery approaches using chromatographic techniques for phytochemical analysis of secondary metabolites such as tannins, alkaloids, and saponins are conducted. Bioassays on micro-organisms are also done during the practical sessions in order to develop the skills for the potential discovery of new antibiotics.
Module content:
Basic principles and methods of plant classification. Sources of plant variation. Modern methods to ascertain evolutionary relationships among plants. The extent and significance of vascular plant diversity. General structural and biological characteristics of evolutionary and ecologically important plant groups. Botanical nomenclature. Plant identification in practice; identification methods, keys, herbaria and botanical gardens. Diagnostic characters for the field identification of trees, wild flowers and grasses. Family recognition of southern African plants. Available literature for plant identification. Methods to conduct floristic surveys. Nature and significance of voucher specimens.
Module content:
Plant genetics and genomics: gene control in plants, epigenetics, co-suppression, forward and reverse genetics, structural and functional genomics. Plant development: flowering, genetics imprinting. Plant-environment interactions. Crop genetic modification: food security, GMO regulation, plant transformation, whole-chromosome transformation, synthetic biology, homologous recombination. Crop molecular markers: marker types, genotyping, QTL mapping, marker-assisted breeding. Future of crop biotechnology: applications of genomics, biopharming, genetical genomics, systems biology
Module content:
Application of modern genetics to human variability, health and disease. Molecular origin of Mendelian and multifactorial diseases. The use of polymorphisms, gene mapping, linkage and association studies in medical genetics. Genetic diagnosis: application of cytogenetic, molecular and genomic techniques. Congenital abnormalities, risk assessment and genetic consultation. Prenatal testing, population screening, treatment of genetic diseases and gene-based therapy. Pharmacogenetics and cancer genetics. Ethical aspects in medical genetics.
Module content:
Introduction to the viruses as a unique kingdom inclusive of their different hosts, especially bacteria, animals and plants; RNA and DNA viruses; viroids, tumour viruses and oncogenes, mechanisms of replication, transcription and protein synthesis; effect on hosts; viral immunology; evolution of viruses.
Module content:
DNA replication and replication control. DNA recombination. DNA damage and repair. Genetics of bacteriophages, plasmids and transposons. Bacterial gene expression control at the transcriptional, translational and post-translational levels. Global regulation and compartmentalisation.
Module content:
Isolation of clonable DNA (genomic libraries, cDNA synthesis) cloning vectors (plasmids, bacteriophages, cosmids) plasmid incompatibility and control of copy number. Ligation of DNA fragments, modification of DNA end and different ligation strategies. Direct and indirect methods for the identification of recombinant organisms. Characterization (polymerase chain reaction, nucleic acid sequencing) and mutagenisis of cloned DNA fragments. Gene expression in Gram negative (E.coli) Gram positive (B.subtilis) and yeast cells (S.cerevisea). Use of Agrobacterium and baculoviruses for gene expression in plant and insect cells respectively. Applications in protein engineering, diagnostics and synthesis of useful products.
Module content:
Interactions between microbes and their abiotic environment; microbial interaction with other strains of the same and other species; microbial interactions across kingdoms; pathogenic interactions between microbes and plant or animal hosts; mutualistic interactions between microbes and their hosts; introduction to systems biology.
Module content:
Principles and examples of plant diseases and their socio-economic importance particularly in the context of Africa and South Africa. Pathogens causing disease of seeds, seedlings, foliage, roots, stems, grains and fruit. Diagnosis, symptom expression and selected disease cycle examples caused by fungi, bacteria, viruses and nematodes.
Module content:
Principles of plant disease control and how it resonates with the sustainable development goals. Non-chemical control including biological control, disease resistance, regulatory measures, cultivation practices, physical methods. Modern chemo-therapy: characteristics, mode of action and application of bioproducts, fungicides, bactericides and nematicides. Principles of integrated disease management. The module will also cover applicable South African legislation, the local crop protection industries and the procedure of registering new chemicals.
Module content:
Mammalian origins and their characteristics: evolution of African mammals; structure and function: integument, support and movement; foods and feeding; environmental adaptations; reproduction; behaviour; ecology and biogeography; social behaviour; sexual selection; parental care and mating systems; community ecology; zoogeography. Special topics: parasites and diseases; domestication and domesticated mammals; conservation. The module addresses the sustainable development goals of Life on Land and Good Health and Well-being.
Module content:
This module focuses on the integration of physiological systems in the context of animal form and function, and the ways in which evolution shapes the physiological processes that determine the energy, water and nutrient fluxes between animals and their environments. Topics covered include: (i) circulation, gas exchange and excretion; (ii) nutritional ecology; (iii) osmoregulation and thermoregulation; and (iv) reproductive physiology. The major focus of this module is to understand the major sources of physiological diversity, namely scaling, phylogenetic inertia, adaptation and phenotypic plasticity, and applying this knowledge to conceptually link physiological processes at the cellular level to macrophysiological patterns at a global scale. Many examples used in this module are directly relevant to the sustainable development goals of Good Health and Well-being, Sustainable Cities and Communities, Climate Action and Life on Land.
Module content:
The extent and significance of insect diversity. Functional insect morphology. The basic principles of taxonomy and the classification of taxa within the Insecta. Insect orders and economically and ecologically important Southern African insect families. Identification of insect orders and families using distinguishing characteristics. General biological and behavioural characteristics of each group. Grouping of insects into similar life-styles and habitats. Examples used in this module are directly relevant to the sustainable development goals of Good Health and Well-being, Sustainable Cities and Communities, Climate Action and Life on Land.
Module content:
This module focuses on the means by which animals can sense and respond to the external and internal environment. Topics covered include: (i) the structure and function of biological membranes; (ii) neurons and nervous systems; (iii) sensing the environment; (iv) glands, hormones and regulation of development and growth; (v) muscles and animal movement and (vi) the initiation and control of behaviour. In line with UN sustainable development goals, the implications of these physiological processes for animal conservation and management will be emphasised. A comparative approach will be adopted throughout the module to highlight the commonalities as well as the ways in which animal lineages have achieved similar functional outcomes from different structural adaptations.
Module content:
The history of behavioural ecology. A causal, developmental, evolutionary and adaptive approach. Sensory systems and communication. Sexual selection, mate choice and sperm competition. Kin selection and group living. Special reference to social insects. The behavioural ecology of humans. Phylogenetic basis of behavioural analysis. The role of behavioural ecology in conservation planning. The module covers sustainable development goals 1-10 and 12-15.
Module content:
Impact of insects on economies, human health and well-being. Protection of crops from insect herbivores through monitoring, forecasting and application of the principles of integrated pest management; epidemiology and modern developments in the control of insect vectors of human and animal diseases; insects as a tool in forensic investigations; ecological and economic significance of insect pollinators and current threats to their survival and health. Lectures will be complemented by practical experiences that provide students with skills in the design, analysis, interpretation and reporting of applied entomological research. Examples used in this module are directly relevant to the sustainable development goals of Life on Land, No Poverty, Zero Hunger and Good Health and Well-being.
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