Programme: BSc Medical Sciences

Kindly take note of the disclaimer regarding qualifications and degree names.
Code Faculty Department
02133407 Faculty of Natural and Agricultural Sciences Department: Anatomy
Credits Duration NQF level
Minimum duration of study: 3 years Total credits: 432 NQF level:  07

Admission requirements

Important information for all prospective students for 2025

The admission requirements below apply to all who apply for admission to the University of Pretoria with a National Senior Certificate (NSC) and Independent Examination Board (IEB) qualifications. Click here for this Faculty Brochure.

Minimum requirements

Achievement level

English Home Language or English First Additional Language

Mathematics

Physical Sciences

APS

NSC/IEB

NSC/IEB

NSC/IEB

5

5

5

32

Only a limited number of places are available in the first year of Bachelor of Science Medical Sciences. Transfers from the extended programme are allowed after three semesters, but only if a student complies with all of the requirements for ANA 121, ANA 122 and ANA 126 (CMY 117 and MLB 111 or equivalent passed).

Life Orientation is excluded when calculating the APS. 

Applicants currently in Grade 12 must apply with their final Grade 11 (or equivalent) results.

Applicants who have completed Grade 12 must apply with their final NSC or equivalent qualification results.

Please note that meeting the minimum academic requirements does not guarantee admission.

Successful candidates will be notified once admitted or conditionally admitted.

Unsuccessful candidates will be notified after 30 June.

Applicants should check their application status regularly on the UP Student Portal at click here.

Applicants with qualifications other than the abovementioned should refer to the International undergraduate prospectus 2025: Applicants with a school leaving certificate not issued by Umalusi (South Africa), available at click here.

International students: Click here.

Transferring students

A transferring student is a student who, at the time of applying at the University of Pretoria (UP) is/was a registered student at another tertiary institution. A transferring student will be considered for admission based on NSC or equivalent qualification and previous academic performance. Students who have been dismissed from other institutions due to poor academic performance will not be considered for admission to UP.

Closing dates: Same as above.

Returning students

A returning student is a student who, at the time of application for a degree programme is/was a registered student at UP, and wants to transfer to another degree at UP. A returning student will be considered for admission based on NSC or equivalent qualification and previous academic performance.

Note:

  • Students who have been excluded/dismissed from a faculty due to poor academic performance may be considered for admission to another programme at UP, as per faculty-specific requirements.
  • Only ONE transfer between UP faculties and TWO transfers within a faculty will be allowed.
  • Admission of returning students will always depend on the faculty concerned and the availability of space in the programmes for which they apply.

Closing date for applications from returning students

Unless capacity allows for an extension of the closing date, applications from returning students must be submitted before the end of August via your UP Student Centre.

Other programme-specific information

1.1    Requirements for specific modules
A candidate who:

  1. does not qualify for STK 110, must enrol for STK 113 and STK 123;
  2. registers for Mathematical Statistics (WST) and Statistics (STK) modules must take note that WST and STK modules, except for STK 281, may not be taken simultaneously in a programme; a student must take one and only one of the following options:
  • WST 111, WST 121, WST 212, WST 211, WST 221, WST 311, WST 312, WST 322, WST 321, and STK 353

or

  • WST 111, WST 121, WST 212, WST 211, WST 221, WST 311, WST 312, WST 322, STK 320, STK 353.

or

  • STK 110, STC 122, STK 210, STK 220, WST 212, STK 310, STK 320, STK 353.
  1. registers for a module presented by another faculty must take note of the timetable clashes, prerequisites for that module, subminimum required in examination papers, supplementary examinations, etc.

1.2    Fundamental modules

  1. It is compulsory for all new first-year students to satisfactorily complete the Academic orientation (UPO 102) and to take Academic information management modules (AIM 111 and AIM 121) and Language and study skills (LST 110). Please see curricula for details.
  2. Students who intend to apply for admission to MBChB or BChD in the second semester, when places become available in those programmes, may be permitted to register for up to 80 module credits and 4 core modules in the first semester during the first year provided that they obtained a final mark of no less than 70% for Grade 12 Mathematics and achieved an APS of 34 or more in the NSC.

Promotion to next study year

A student will be promoted to the following year of study if he or she passed 100 credits of the prescribed credits for a year of study, unless the Dean on the recommendation of the relevant head of department decides otherwise. A student who does not comply with the requirements for promotion to the following year of study, retains the credit for the modules already passed and may be admitted by the Dean, on recommendation of the relevant head of department, to modules of the following year of study to a maximum of 48 credits, provided that it will fit in with both the lecture and examination timetable.

General promotion requirements in the faculty
All students whose academic progress is not acceptable can be suspended from further studies.

  • A student who is excluded from further studies in terms of the stipulations of the abovementioned regulations, will be notified in writing by the Dean or Admissions Committee at the end of the relevant semester.
  • A student who has been excluded from further studies may apply in writing to the Admissions Committee of the Faculty of Natural and Agricultural Sciences for re-admission.
  • Should the student be re-admitted by the Admissions Committee, strict conditions will be set which the student must comply with in order to proceed with his/her studies.
  • Should the student not be re-admitted to further studies by the Admissions Committee, he/she will be informed in writing.
  • Students who are not re-admitted by the Admissions Committee have the right to appeal to the Senate Appeals Committee.
  • Any decision taken by the Senate Appeals Committee is final.

Minimum credits: 142

Fundamental =   14
Core              =   130

Additional information:

  • Please note: Students who have not passed all the first year, first-semester modules in BSc MedSci are excluded from continuing with BSc MedSci in the second semester and need to change to another BSc programme.

Fundamental modules

Core modules

  • Module content:

    Terminology, musculo-skeletal system, nervous system, surface anatomy, cardiovascular system, respiratory system, urogenital system, gastro-intestinal system, endocrine system, introductory osteology and joints, introductory embryology.

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  • Module content:

    Introduction to osteology, bone function and classification, humerus, radius, ulna, femur, tibia, fibula, clavicle, scapula, ribs, sternum, vertebrae, pelvis, hand and foot bones, sesamoid bones, skull, mandible, joints.

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  • Module content:

    General introduction to cells and tissue, terminology, the cell and cytoplasm, organelles and inclusions, surface and glandular epithelium, general connective tissue, specialised connective tissue, namely cartilage, bone, blood and haemopoietic tissue, muscle and nervous tissue.

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  • Module content:

    Simple statistical analysis: Data collection and analysis: Samples, tabulation, graphical representation, describing location, spread and skewness. Introductory probability and distribution theory. Sampling distributions and the central limit theorem. Statistical inference: Basic principles, estimation and testing in the one- and two-sample cases (parametric and non-parametric). Introduction to experimental design. One- and twoway designs, randomised blocks. Multiple statistical analysis: Bivariate data sets: Curve fitting (linear and non-linear), growth curves. Statistical inference in the simple regression case. Categorical analysis: Testing goodness of fit and contingency tables. Multiple regression and correlation: Fitting and testing of models. Residual analysis. Computer literacy: Use of computer packages in data analysis and report writing.

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  • Module content:

    General introduction to inorganic, analytical and physical chemistry. Atomic structure and periodicity. Molecular structure and chemical bonding using the VSEPR-model. Nomenclature of inorganic ions and compounds. Classification of reactions: precipitation, acid-base, redox reactions and gas-forming reactions. Mole concept and stoichiometric calculations concerning chemical formulas and chemical reactions. Principles of reactivity: energy and chemical reactions. Physical behaviour gases, liquids, solids and solutions and the role of intermolecular forces. Rate of reactions: Introduction to chemical kinetics.

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  • Module content:

    Theory: General physical-analytical chemistry: Chemical equilibrium, acids and bases, buffers, solubility equilibrium, entropy and free energy, electrochemistry. Organic chemistry: Structure (bonding), nomenclature, isomerism, introductory stereochemistry, introduction to chemical reactions and chemical properties of organic compounds and biological compounds, i.e. carbohydrates and aminoacids. Practical: Molecular structure (model building), synthesis and properties of simple organic compounds.

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  • Module content:

    This module consists of two components: first, a philosophy of science component which provides an introduction to scientific reasoning and philosophical debates on scientific method; and secondly, a philosophy of medicine component which focuses on the relation between causation and the concept of disease and on the nature of evidence-based medicine.

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  • Module content:

    Chromosomes and cell division. Principles of Mendelian inheritance: locus and alleles, dominance interactions, extensions and modifications of basic principles.. Probability studies. Sex determination and sex linked traits. Pedigree analysis. Genetic linkage and chromosome mapping. Chromosome variation.

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  • Module content:

    The module will introduce the student to the field of Microbiology. Basic Microbiological aspects that will be covered include introduction into the diversity of the microbial world (bacteria, archaea, eukaryotic microorganisms and viruses), basic principles of cell structure and function, microbial nutrition and microbial growth and growth control. Applications in Microbiology will be illustrated by specific examples i.e. bioremediation, animal-microbial symbiosis, plant-microbial symbiosis and the use of microorganisms in industrial microbiology. Wastewater treatment, microbial diseases and food will be introduced using specific examples.

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  • Module content:

     Introduction to the molecular structure and function of the cell. Basic chemistry of the cell. Structure and composition of prokaryotic and eukaryotic cells. Ultrastructure and function of cellular organelles, membranes and the cytoskeleton. General principles of energy, enzymes and cell metabolism. Selected processes, e.g. glycolysis, respiration and/or photosynthesis. Introduction to molecular genetics: DNA structure and replication, transcription, translation. Cell growth and cell division.

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  • Module content:

    Note: PHY 131 is aimed at students who will not continue with physics. PHY 131 cannot be used as a substitute for PHY 114.

    Units, vectors, one dimensional kinematics, dynamics, work, equilibrium, sound, liquids, heat, thermodynamic processes, electric potential and capacitance, direct current and alternating current, optics, modern physics, radioactivity.

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  • Module content:

    *Students will not be credited for more than one of the following modules for their degree: WTW 134, WTW 165, WTW 114, WTW 158. WTW 134 does not lead to admission to Mathematics at 200 level and is intended for students who require Mathematics at 100 level only. WTW 134 is offered as WTW 165 in the second semester only to students who have applied in the first semester of the current year for the approximately 65 MBChB, or the 5-6 BChD places becoming available in the second semester and who were therefore enrolled for MGW 112 in the first semester of the current year. 
    Functions, derivatives, interpretation of the derivative, rules of differentiation, applications of differentiation, integration, interpretation of the definite integral, applications of integration. Matrices, solutions of systems of equations. All topics are studied in the context of applications.

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  • Module content:

    *Students will not be credited for more than one of the following modules for their degree: WTW 134, WTW 165, WTW 114, WTW 158. WTW 165 does not lead to Mathematics at 200 level and is intended for students who require Mathematics at 100 level only. WTW 165 is offered in English in the second semester only to students who have applied in the first semester of the current year for the approximately 65 MBChB, or the 5-6 BChD places becoming available in the second semester and who were therefore enrolled for MGW 112 in the first semester of the current year.

    Functions, derivatives, interpretation of the derivative, rules of differentiation, applications of differentiation, integration, interpretation of the definite integral, applications of integration, matrices, solutions of systems of equations. All topics are studied in the context of applications.

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Minimum credits: 144

Core = 96
Elective = 48

Additional information:

  • FLG option: 48 credits, GTS option: 48 credits, FAR option: same as FLG option
  • ANA + FLG option: First semester FLG 211 (12) and FLG 212 (12) second semester FLG 221 (12) and FLG 222 (12)
  • ANA + GTS option: First semester GTS 251 (12) and MBY 251 (12), second semester GTS 261 (12) and MBY 261 (12)
  • ANA + FLG/FAR option only in Final year: Same as FLG option

Core modules

  • Module content:

    Functional review of the cell and cell content. Normal and abnormal cell function in relation to structure. Control of the human cell, heredity and the human genome. Cell communication, growth and development, adhesion and division. Aspects of cellular research. Techniques on how to study cells. Medical cell and molecular biology application.
    NOTE: This module is not open to all students and may only be taken by BSc (Medical Sciences) students.

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  • Module content:

    Introduction to paleoanthropology, focusing on hominid fossil record, principles of evolution, principles of heredity, human variation, introduction to primatology, hominid taxonomy, time-frames and dating methods, fossilisation and taphonomy, trends in hominid evolution, hominid sites. Australopithecus, homo habilis, homo erectus, homo sapiens neanderthalensis, the origin of anatomically modern human beings, DNA studies, palaeo-environments, hominid diets, introduction to the development of culture, South African populations, human adaptation and modernisation.

    NOTE: This module is not open to all students and may only be taken by BSc (Medical Sciences) students.

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  • Module content:

    General introduction to organ structure.
    Terminology. The eye, ear, skin, circulatory system, nervous system, lymphoid system, gastrointestinal tract, gastrointestinal tract glands, respiratory system, urinary system, male and female reproductive systems, endocrine system.
    NOTE: This module is not open to all students and may only be taken by BSc (Medical Sciences) students.

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  • Module content:

    Regional approach to human anatomy. Cadaver dissection of the head, neck as well as neuro-anatomy. Anatomical techniques. 

    NOTE: This module is not open to all students and may only be taken by BSc (Medical Sciences) students.

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  • Module content:

    Structural and ionic properties of amino acids. Peptides, the peptide bond, primary, secondary, tertiary and quaternary structure of proteins. Interactions that stabilise protein structure, denaturation and renaturation of proteins. Introduction to methods for the purification of proteins, amino acid composition, and sequence determinations. Enzyme kinetics and enzyme inhibition. Allosteric enzymes, regulation of enzyme activity, active centres and mechanisms of enzyme catalysis. Examples of industrial applications of enzymes and in clinical pathology as biomarkers of diseases. Online activities include introduction to practical laboratory techniques and Good Laboratory Practice; techniques for the quantitative and qualitative analysis of biological molecules; enzyme activity measurements; processing and presentation of scientific data.

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  • Module content:

    Carbohydrate structure and function. Blood glucose measurement in the diagnosis and treatment of diabetes. Bioenergetics and biochemical reaction types. Glycolysis,  gluconeogenesis, glycogen metabolism, pentose phosphate pathway, citric acid cycle and electron transport. Total ATP yield from the complete oxidation of glucose. A comparison of cellular respiration and photosynthesis. Online activities include techniques for the study and analysis of metabolic pathways and enzymes; PO ratio of mitochondria, electrophoresis, extraction, solubility and gel permeation techniques; scientific method and design. 

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  • Module content:

    Chemical foundations. Weak interactions in aqueous systems. Ionisation of water, weak acids and weak bases. Buffering against pH changes in biological systems. Water as a reactant and function of water. Carbohydrate structure and function. Biochemistry of lipids and membrane structure. Nucleotides and nucleic acids. Other functions of nucleotides: energy carriers, components of enzyme cofactors and chemical messengers. Introduction to metabolism. Bioenergetics and biochemical reaction types. Online activities include introduction to laboratory safety and Good Laboratory Practice; basic biochemical calculations; experimental method design and scientific controls, processing and presentation of scientific data.

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  • Module content:

    Biochemistry of lipids, membrane structure, anabolism and catabolism of lipids.  Total ATP yield from the complete catabolism of lipids. Electron transport chain and energy production through oxidative phosphorylation. Nitrogen metabolism, amino acid biosynthesis and catabolism. Biosynthesis of neurotransmitters, pigments, hormones and nucleotides from amino acids. Catabolism of purines and pyrimidines. Therapeutic agents directed against nucleotide metabolism. Examples of inborn errors of metabolism of nitrogen containing compounds. The urea cycle, nitrogen excretion. Online activities include training in scientific reading skills; evaluation of a scientific report; techniques for separation analysis and visualisation of biological molecules; hypothesis design and testing, method design and scientific controls.

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Elective modules

  • Module content:

    Orientation in physiology, homeostasis, cells and tissue, muscle and neurophysiology, cerebrospinal fluid and the special senses.
    Practical work: Practical exercises to complement the theory.

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  • Module content:

    Body fluids; haematology; cardiovascular physiology and the lymphatic system. Practical work: Practical exercises to complement the theory.

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  • Module content:

    Structure, gas exchange and non-respiratory functions of the lungs; structure, excretory and non-urinary functions of the kidneys, acid-base balance, as well as the skin and body temperature control.
    Practical work: Practical exercises to complement the theory.

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  • Module content:

    Nutrition, digestion and metabolism; hormonal control of the body functions and the reproductive systems. Practical work: Practical exercises to complement the theory.

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  • Module content:

    The chemical nature of DNA. The processes of DNA replication, transcription, RNA processing, translation. Control of gene expression in prokaryotes and eukaryotes.  Recombinant DNA technology and its applications in gene analysis and manipulation.

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  • Module content:

    Chromosome structure and transposable elements. Mutation and DNA repair. Genomics and proteomics. Organelle genomes. Introduction to genetic analysis of populations: allele and genotypic frequencies, Hardy Weinberg Law, its extensions and implications for different mating systems. Introduction to quantitative and evolutionary genetics.

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  • Module content:

    Growth, replication and survival of bacteria, Energy sources, harvesting from light versus oxidation, regulation of catabolic pathways, chemotaxis. Nitrogen metabolism, iron-scavenging. Alternative electron acceptors: denitrification, sulphate reduction, methanogenesis.  Bacterial evolution, systematic and genomics. Biodiversity; bacteria occurring in the natural environment (soil, water and air), associated with humans, animals, plants, and those of importance in foods and in the water industry.

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  • Module content:

    Organisation and molecular architecture of fungal thalli, chemistry of the fungal cell. Chemical and physiological requirements for growth and nutrient acquisition. Mating and meiosis; spore development; spore dormancy, dispersal and germination. Fungi as saprobes in soil, air, plant, aquatic and marine ecosystems; role of fungi as decomposers and in the deterioration of materials; fungi as predators and parasites; mycoses, mycetisms and mycotoxicoses; fungi as symbionts of plants, insects and animals. Applications of fungi in biotechnology.

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Minimum credits: 144

Core = 72
Elective = 72

Additional information:
Elective credits:

  • FLG option: 72 credits, GTS option: 72 credits, FLG/FAR option: 72 credits
  • ANA + FLG option: First semester FLG 330 (18) and FLG 327 (18), second semester FLG 331 (18) and FLG 332 (18)
  • ANA+ GTS option: First semester GTS 351 (18) and GTS 367 (18), second semester GTS 354 (18) and GTS 368 (18)
  • ANA+ FLG/FAR option: First semester FLG 330 (18) and FAR 381 (18), second semester FLG 331 (18) or FLG 332 (18) and FAR 382 (18)

Core modules

  • Module content:

    Introduction to forensic anthropology, detection of graves, excavation of graves, human vs. animal bone, forensic entomology, osteometry, cranial and post-cranial measurements, non-metric features of the skeleton, age determination, sex determination, race determination, ante-mortem stature, dental analysis, osteopathology, factors of individualisation, measurements of the face, introduction to face mapping and skull-photo superimposition, legal aspects. NOTE: This module is not open to all students and may only be taken by BSc (Medical Sciences) students.

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  • Module content:

    General introduction to light and electron microscopic techniques: fixation, processing, imbedding, staining. Principles of different staining techniques for LM and EM: routine stains, proteins, carbohydrates, amino acids, metachromasia, immunocytochemistry, lectin stains, specialised stains. Principles of the operation of LM and EM: general LM, fluorescent microscopy, differential contrast microscopy, dark field microscopy, phase contrast microscopy, transmission and scanning electron microscopy.

    NOTE: This module is not open to all students and may only be taken by BSc (Medical Sciences) students.

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  • Module content:

    Practical aspects of cell biology. Cell, tissue, organ, and organism culture. The biology of the culture environment. Cellular basic of morphogenesis, cleavage patterns and gastrulation. The early vertebrate development; neurilation, ecto-, meso- and endoderm derivatives. Cell destiny and embryonic axis including malformations. Development of the tetrapod limb and cell death. Cell interactions at a distance through hormones and metamorphosis.
    NOTE: This module is not open to all students and may only be taken by BSc (Medical Sciences) students.

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  • Module content:

    Regional approach to human anatomy.
    Cadaver dissection of the head, neck as well as neuro-anatomy. Anatomical techniques.
    NOTE: This module is not open to all students and may only be taken by BSc (Medical Sciences) students.

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Elective modules

  • Module content:

    The undergraduate pharmacology module introduces students to general pharmacological principles, routes of administration, pharmacokinetics and pharmacodynamics. Furthermore, disease treatment with relation to disorders of the cardiovascular, inflammatory and autonomic nervous system is discussed, as well as anaesthesia, asthma, diabetes, diuresis, obesity and pain.

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  • Module content:

    Hormones, drugs that act on the histaminergic, serotonergic, and dopaminergic receptors. Pharmacotherapy of diabetes mellitus, schizophrenia, depression, obesity, anxiety, insomnia, gastro-intestinal diseases. Anticoagulants, antimicrobial drugs.

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  • Module content:

    Overview of higher cognitive functions and the relations between psyche, brain and the immune system. Practical work: Applied practical work with specific examples drawn from South African case studies taught within the framework of the UN Sustainable Development Goal 3 (Good Health and Well-being).

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  • Module content:

    During this module the biology of cellular processes such as the cell cycle, cell death, migration and their related cellular signalling pathways will be discussed as well as their role in early stage embryology and age-related pathologies. Practical work: Exposure to applied molecular biology techniques with specific examples drawn from South African case studies taught within the framework of the UN Sustainable Development Goal of Good Health and Well-being (Sustainable Development Goal 3).

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  • Module content:

    Mechanisms of muscle contraction and energy sources. Cardio-respiratory changes, thermo-regulation and other adjustments during exercise. Use and misuse of substances to improve performance. Practical work: Applied practical work with exercise descriptions for the South African context taught within the framework of the UN Sustainable Development Goal 3 (Good Health and Well-being).

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  • Module content:

    Integration of all the human physiological systems. Practical work: Applied practical work.

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  • Module content:

    Regulation of gene expression in eukaryotes: regulation at the genome, transcription, RNA processing and translation levels. DNA elements and protein factors involved in gene control. The role of chromatin structure and epigenetic changes. Technology and experimental approaches used in studying eukaryotic gene control. Applications of the principles of gene control in eg cell signaling pathways, development cancer and other diseases in humans.

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  • Module content:

    A unifying framework for biology. Mechanisms involved in the evolution of genes, genomes and species. Comparative genomics across the kingdoms of life. Phylogenetic inference. Applications of phylogenetics and evolutionary genomics research, including relevance to sustainable development goals for food security, good health and the biosphere.

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  • Module content:

    Processes that affect genetic evolution: mutation, drift, natural selection and recombination. Fisher-Wright and coalescence models. Groupings of genes: linkage, inbreeding, population structure and gene flow. Neutral and nearly neutral theory. Quantitative genetics and the phenotype. Optimality. Adaptation. Levels of selection in sex ratios and conflict. Reproductive value and life history. Relatedness and kin selection. Sexual reproduction and selection. Genomic complexity and neutrality.

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  • Module content:

    Application of modern genetics to human variability, health and disease. Molecular origin of Mendelian and multifactorial diseases. The use of polymorphisms, gene mapping, linkage and association studies in medical genetics. Genetic diagnosis: application of cytogenetic, molecular and genomic techniques. Congenital abnormalities, risk assessment and genetic consultation. Prenatal testing, population screening, treatment of genetic diseases and gene-based therapy. Pharmacogenetics and cancer genetics. Ethical aspects in medical genetics.

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General Academic Regulations and Student Rules
The General Academic Regulations (G Regulations) and General Student Rules apply to all faculties and registered students of the University, as well as all prospective students who have accepted an offer of a place at the University of Pretoria. On registering for a programme, the student bears the responsibility of ensuring that they familiarise themselves with the General Academic Regulations applicable to their registration, as well as the relevant faculty-specific and programme-specific regulations and information as stipulated in the relevant yearbook. Ignorance concerning these regulations will not be accepted as an excuse for any transgression, or basis for an exception to any of the aforementioned regulations. The G Regulations are updated annually and may be amended after the publication of this information.

Regulations, degree requirements and information
The faculty regulations, information on and requirements for the degrees published here are subject to change and may be amended after the publication of this information.

University of Pretoria Programme Qualification Mix (PQM) verification project
The higher education sector has undergone an extensive alignment to the Higher Education Qualification Sub-Framework (HEQSF) across all institutions in South Africa. In order to comply with the HEQSF, all institutions are legally required to participate in a national initiative led by regulatory bodies such as the Department of Higher Education and Training (DHET), the Council on Higher Education (CHE), and the South African Qualifications Authority (SAQA). The University of Pretoria is presently engaged in an ongoing effort to align its qualifications and programmes with the HEQSF criteria. Current and prospective students should take note that changes to UP qualification and programme names, may occur as a result of the HEQSF initiative. Students are advised to contact their faculties if they have any questions.

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